Senior Scientific Staff
Andrew Cherniack, PhD
Group Leader, Computational Biology
2010-
PhD, The Ohio State University
Phone|Email
My group at the Broad and Dana-Farber is involved in three different efforts:
1) Along with Dr. Rameen Beroukhim, we lead efforts to analyze copy number alterations and rearrangements for the National Cancer Institute’s Genomic Data Analysis Network (GDAN).
2) We provide computational biology support for new target discovery and biomarker development for cancer therapeutics projects at the Broad Institute.
3) We collaborate with physicians and scientists across Dana-Farber on research projects utilizing clinical targeted sequencing data.
Group Leader, Computational Biology
2010-
PhD, The Ohio State University
Phone|Email
My group at the Broad and Dana-Farber is involved in three different efforts:
1) Along with Dr. Rameen Beroukhim, we lead efforts to analyze copy number alterations and rearrangements for the National Cancer Institute’s Genomic Data Analysis Network (GDAN).
2) We provide computational biology support for new target discovery and biomarker development for cancer therapeutics projects at the Broad Institute.
3) We collaborate with physicians and scientists across Dana-Farber on research projects utilizing clinical targeted sequencing data.
Jon Goldstein, PhD
Research Scientist II
2014-
PhD, University of Wisconsin - Madison
Phone|Email|LinkedIn
My focus is to understand the biochemical and cellular consequences of genomic alterations in cancer. My goal is to translate these findings into targeted therapeutic candidates.
Research Scientist II
2014-
PhD, University of Wisconsin - Madison
Phone|Email|LinkedIn
My focus is to understand the biochemical and cellular consequences of genomic alterations in cancer. My goal is to translate these findings into targeted therapeutic candidates.
Heidi Greulich, PhD
Senior Group Leader/Director, Cancer Therapeutic Projects
2004-
PhD, The Rockefeller University
Phone|Email|LinkedIn
My group studies therapeutic targets identified from cancer genomic data with the goal of developing new cancer treatments. Target classes include mutated receptor tyrosine kinases, epigenetic targets, and small molecules that cause complex formation between PDE3A and SLFN12, inducing death of cancer cells expressing elevated levels of these two proteins.
Senior Group Leader/Director, Cancer Therapeutic Projects
2004-
PhD, The Rockefeller University
Phone|Email|LinkedIn
My group studies therapeutic targets identified from cancer genomic data with the goal of developing new cancer treatments. Target classes include mutated receptor tyrosine kinases, epigenetic targets, and small molecules that cause complex formation between PDE3A and SLFN12, inducing death of cancer cells expressing elevated levels of these two proteins.
Jodi Hirschman, PhD
Research Program Manager
2019-
PhD, University of California, Davis
Email|LinkedIn
I am the Research Program Manager both for the Meyerson laboratory and for Grand Challenge OPTIMISTICC project. For the former, I help with the writing and submission of research proposals and other communications; for the OPTIMISTICC project, I coordinate communications and events for the 13-lab consortium, and assist with scientific strategy.
Research Program Manager
2019-
PhD, University of California, Davis
Email|LinkedIn
I am the Research Program Manager both for the Meyerson laboratory and for Grand Challenge OPTIMISTICC project. For the former, I help with the writing and submission of research proposals and other communications; for the OPTIMISTICC project, I coordinate communications and events for the 13-lab consortium, and assist with scientific strategy.
Brian Golbourn, PhD
Research Scientist II
2022-
PhD, University of Toronto - Brain Tumor Research Center
My research focus is the development of biochemical and cellular-based assays to study interactions between protein and DNA that are essential to cancer cell survival. Outside of the lab I enjoy biking, fishing, and snowboarding.
Research Scientist II
2022-
PhD, University of Toronto - Brain Tumor Research Center
My research focus is the development of biochemical and cellular-based assays to study interactions between protein and DNA that are essential to cancer cell survival. Outside of the lab I enjoy biking, fishing, and snowboarding.
Kristyna Kotynkova, PhD
Research Scientist I
2022-
PhD, University College London (Francis Crick Institute)
I am studying the mechanism of novel cancer therapeutics that target tumor cells expressing high levels of PDE3A and SLFN12. Outside the lab, I enjoy hiking, birding and rock climbing.
Research Scientist I
2022-
PhD, University College London (Francis Crick Institute)
I am studying the mechanism of novel cancer therapeutics that target tumor cells expressing high levels of PDE3A and SLFN12. Outside the lab, I enjoy hiking, birding and rock climbing.
Sooncheol (Charlie) Lee, PhD
Research Scientist II
2020-
PhD, Korea Advanced Institute of Science and Technology, South Korea
Phone|Email|LinkedIn
My research focuses on how RNA-binding proteins regulate gene expression post-transcriptionally and their role in the survival of cancer cells. My long-term goal is to induce apoptosis of cancer cells by targeting RNA-binding proteins or post-transcriptional regulation.
Research Scientist II
2020-
PhD, Korea Advanced Institute of Science and Technology, South Korea
Phone|Email|LinkedIn
My research focuses on how RNA-binding proteins regulate gene expression post-transcriptionally and their role in the survival of cancer cells. My long-term goal is to induce apoptosis of cancer cells by targeting RNA-binding proteins or post-transcriptional regulation.
Yvonne Li, PhD, FACMG
PhD, University of British Columbia, Canada
I collaborate with DFCI oncologists to leverage Profile OncoPanel targeted panel sequencing data for genomic analysis and clinical correlation.
PhD, University of British Columbia, Canada
I collaborate with DFCI oncologists to leverage Profile OncoPanel targeted panel sequencing data for genomic analysis and clinical correlation.
Gizem Karsli Uzunbas, PhD
Research Scientists II
2019-
PhD, Rutgers University
Email|LinkedIn
My research goal is to develop new therapeutic approaches to treat lung cancers with mutations identified by tumor sequencing.
Research Scientists II
2019-
PhD, Rutgers University
Email|LinkedIn
My research goal is to develop new therapeutic approaches to treat lung cancers with mutations identified by tumor sequencing.
Junior Scientific Staff
Sawyer Andersen, B.S.
Research Associate
2022-
B.S., University of Massachusetts Amherst
I am working to understand the mechanisms of novel cancer therapeutics that target tumor cells expressing high levels of SLFN12.
Research Associate
2022-
B.S., University of Massachusetts Amherst
I am working to understand the mechanisms of novel cancer therapeutics that target tumor cells expressing high levels of SLFN12.
Hersh Gupta, A.B.
Associate Computational Biologist
2020-
B.A., Brown University
I work with physicians across DFCI, the Broad, and other organizations to analyze clinical targeted sequencing data using OncoPanel. I focus on the use of rigorous computational and statistical methods to answer both clinical and basic science questions.
Associate Computational Biologist
2020-
B.A., Brown University
I work with physicians across DFCI, the Broad, and other organizations to analyze clinical targeted sequencing data using OncoPanel. I focus on the use of rigorous computational and statistical methods to answer both clinical and basic science questions.
Stephanie Hoyt, B.A.
Associate Computational Biologist
2020-
B.A., Cornell University
I work on the discovery of new targets for cancer treatments.
Associate Computational Biologist
2020-
B.A., Cornell University
I work on the discovery of new targets for cancer treatments.
Lauren Kageler, B.S.
Research Associate
2020-
B.S., Dickinson College
My work is focused on validating telomerase as a therapeutic target in models of glioblastoma and other cancer types; and generating novel biochemical tools for a telomerase drug discovery effort.
Research Associate
2020-
B.S., Dickinson College
My work is focused on validating telomerase as a therapeutic target in models of glioblastoma and other cancer types; and generating novel biochemical tools for a telomerase drug discovery effort.
Lior Kofman, B.S.
Associate Computational Biologist
2021-
B.S., Tufts University
I am currently working on determining the influence of the microbiome on outcomes of various cancers and analyzing clinical sequencing data.
Associate Computational Biologist
2021-
B.S., Tufts University
I am currently working on determining the influence of the microbiome on outcomes of various cancers and analyzing clinical sequencing data.
Joseph McGaunn, B.S.
Research Associate
2020-
B.S., University of Massachusetts Amherst
Email|LinkedIn|Twitter
I am working to understand the mechanism of action of novel cancer therapeutics and identify patient populations that may benefit from these drugs. One of my current focuses is a novel class of small molecules that target cancers expressing high levels of PDE3A and SLFN12. In addition, I am also exploring small molecules that target epigenetic regulators.
Research Associate
2020-
B.S., University of Massachusetts Amherst
Email|LinkedIn|Twitter
I am working to understand the mechanism of action of novel cancer therapeutics and identify patient populations that may benefit from these drugs. One of my current focuses is a novel class of small molecules that target cancers expressing high levels of PDE3A and SLFN12. In addition, I am also exploring small molecules that target epigenetic regulators.
Quinn McVeigh, B.A.
Research Associate
2021-
B.A., Carleton College
My work aims to develop novel targeting approaches to lung cancer using targets identified from genomic analysis.
Research Associate
2021-
B.A., Carleton College
My work aims to develop novel targeting approaches to lung cancer using targets identified from genomic analysis.
Zarin Mohsenin, B.S.
Research Technician
2021-
B.S., Haverford College
I am interested in elucidating the function of the gene Cmtr2 and its role in lung cancer.
Research Technician
2021-
B.S., Haverford College
I am interested in elucidating the function of the gene Cmtr2 and its role in lung cancer.
Brianna Silverman, B.S.
Research Technician
2019-
B.S., Brandeis University
I assist in experiments focused on uncovering mechanisms of resistance to receptor tyrosine kinase inhibitors in lung cancer. I am currently investigating resistance and sensitivity to EGFR inhibitors.
Research Technician
2019-
B.S., Brandeis University
I assist in experiments focused on uncovering mechanisms of resistance to receptor tyrosine kinase inhibitors in lung cancer. I am currently investigating resistance and sensitivity to EGFR inhibitors.
Stephanie Tang, A.B.
Research Associate
2020-
A.B., Harvard College
I am interested in exploring the genetic underpinnings of cancer and translating these findings into potential therapies.
Research Associate
2020-
A.B., Harvard College
I am interested in exploring the genetic underpinnings of cancer and translating these findings into potential therapies.
Patrick Zhuang, B.A.
Research Technician
2021-
B.A., Williams College
I have a background in chemistry. I'm interested in developing novel therapeutic strategies to target innate immune signaling pathways that regulate cancer cell viability.
Research Technician
2021-
B.A., Williams College
I have a background in chemistry. I'm interested in developing novel therapeutic strategies to target innate immune signaling pathways that regulate cancer cell viability.