Primary Articles

Primary articles are original research publications where a member of the Meyerson laboratory is either first, co-first, corresponding or co-corresponding author. Please email us for a reprint of any of our papers.

2023

Aquilanti et al. Telomerase inhibition is an effective therapeutic strategy in TERT promoter mutant-glioblastoma models with low tumor volume. Neuro Oncol. 2023 Jan 24:noad024.
Orsi et al. Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists. Bioorg Med Chem. 2023 Jan 15;78:117130.

2022

Freeman et al. Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma. Cell Rep Med. 2022 Feb 15;3(2):100500.
Gao et al. Tangent normalization for somatic copy-number inference in cancer genome analysis. Bioinformatics. 2022 Oct 14;38(20):4677-4686.
Lee et al. Velcrin-induced selective cleavage of tRNALeu(TAA) by SLFN12 causes cancer cell death. Nat Chem Biol. 2022 Oct 27.
Mäkinen, Zhou, Zhang et al. Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors. Genome Med. 2022 Aug 3;14(1):82.
Nomburg et al. Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses. PLoS Pathog. 2022 Apr 1;18(4).
Nomburg et al. An international report on bacterial communities in esophageal squamous cell carcinoma. Int J Cancer. 2022 Dec 1;151(11):1947-1959.
Orsi et al. Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069. J Med Chem. 2022 Oct 21.
Tan, Slevin, Meyerson, Li. Identifying and correcting repeat-calling errors in nanopore sequencing of telomeres. Genome Biol. 2022 Aug 26;23(1):180.
Zhang, Golomb, Meyerson. Functional genomic analysis of CDK4 and CDK6 gene dependency across human cancer cell lines. Cancer Res. 2022 Apr 8:canres.2428.2021.
Zhou et al. Patterns of structural variation define prostate cancer across disease states. JCI Insight. 2022 Aug 9:e161370.

2021

Carrot-Zhang et al. Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway. Cell Rep. 2021 Feb 2;34(5).
Carrot-Zhang et al. Analytical protocol to identify local ancestry-associated molecular features in cancer. STAR Protoc. 2021 Sep 20;2(4):100766.
Garvie et al. Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase. Nature Communications. 2021 Jul 16;12(1):4375.
Lee & Meyerson. Antigen identification for HLA class I– and HLA class II–restricted T cell receptors using cytokine-capturing antigen-presenting cells. Science Immunology. 2021 Jan 22;6(55).
Mäkinen, Zhou, et al. Genomic evolution in a patient with lung adenocarcinoma with a germline EGFR T790M mutation. JTO Clinical and Research Reports. 2021 Apr 1;2(4).
Spurr et al. Quantification of aneuploidy in targeted sequencing data using ASCETS. Bioinformatics. 2021 Aug 25;37(16):2461-2463.
Tan et al. Haplotype-resolved germline and somatic alterations in renal medullary carcinomas. Genome Med. 2021 Jul 14;13(1):114.
Zhou, Wu, Zhang et al. Pan-ERBB kinase inhibition augments CDK4/6 inhibitor efficacy in oesophageal squamous cell carcinoma. Gut. 2021 Mar 31:gutjnl-2020-323276.

2020

Carrot-Zhang et al. Comprehensive analysis of genetic ancestry and its molecular correlates in cancer. Cancer Cell. 2020 May 11;37(5):639-654.
Carrot-Zhang et al. Genetic ancestry contributes to somatic mutations in lung cancers from admixed Latin American populations. Cancer Discov. 2020 Dec 2:CD-20-1165.
Lamberti, Spurr et al. Clinicopathological and genomic correlates of programmed cell death ligand 1 (PD-L1) expression in nonsquamous non-small-cell lung cancer. Ann Oncol. 2020 Apr 27. pii: S0923-7534(20)36078-6.
Llabata et al. Multi-Omics analysis identifies MGA as a negative regulator of the MYC pathway in lung adenocarcinoma. Mol Cancer Res. 2020 Apr;18(4):574-584.
Nomburg, Bullman et al. Comprehensive metagenomic analysis of blastic plasmacytoid dendritic cell neoplasm. Blood Adv. 2020 Mar 24;4(6):1006-1011.
Nomburg, Meyerson, & DeCaprio. Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2. Genome Med. 2020 Nov 9;12(108).
Touat, Li et al. Mechanisms and therapeutic implications of hypermutation in gliomas . Nature. 2020 Apr;580(7804):517-523.
Wu et al. Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. J Biol Chem. 2020 Mar 13;295(11):3431-3446.
Zhang, Mäkinen, et al. Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors. Genes Chromosomes Cancer. 2020 Apr 14. PMID: 32291827.

2019

Cai, Choi, Gelbard, & Meyerson. Identification and characterization of oncogenic SOS1 mutations in lung adenocarcinoma. Mol Cancer Res. 2019 Apr;17(4):1002-1012.
Chen, Carrot-Zhang et al. Genomic and immune profiling of pre-invasive lung adenocarcinoma. Nat Commun. 2019 Nov 29;10(1):5472.
Hayes et al. A functional landscape of resistance to MEK1/2 and CDK4/6 inhibition in NRAS-mutant melanoma. Cancer Res. 2019 05 01; 79(9):2352-2366.
Lewis, de Waal, Wu et al. Optimization of PDE3A modulators for SLFN12-dependent cancer cell killing. ACS Med Chem Lett. 2019 Nov 14; 10(11):1537-1542.
Stover, Baco, Cohen, Li et al. Pooled genomic screens identify anti-apoptotic genes as targetable mediators of chemotherapy resistance in ovarian cancer. Mol Cancer Res. 2019 11; 17(11):2281-2293.

2018

Gannon, Zou et al. Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells. Nat Commun. 2018 Dec 21;9(1):5450.
Taylor, Shih, Ha et al. Genomic and functional approaches to understanding cancer aneuploidy. Cancer Cell. 2018 Apr 9;33(4):676-689.e3.
Viswanathan et al. Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer. Nat Genet. 2018 07; 50(7):937-943.
Viswanathan, Ha, Hoff et al. Structural alterations driving castration-resistant prostate cancer revealed by linked-read genome sequencing. Cell. 2018 Jul 12;174(2):433-447.e19.
Walker et al. GATK PathSeq: a customizable computational tool for the discovery and identification of microbial sequences in libraries from eukaryotic hosts. Bioinformatics. 2018 Dec 15;34(24):4287-4289.
Zhang, Choi et al. Somatic superenhancer duplications and hotspot mutations lead to oncogenic activation of the KLF5 transcription factor. Cancer Discov. 2018 Jan;8(1):108-125.

2017

Adalsteinsson, Ha, Freeman et al. Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. Nat Commun. 2017 Nov 6;8(1):1324.
Bullman, Pedamallu et al. Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer. Science 2017 Dec 15;358(6369):1443-1448.
Campbell et al. Comparison of prevalence and types of mutations in lung cancers among black and white populations. JAMA Oncol. 2017 Jun 1;3(6):801-809.
Cherniack et al. Integrated molecular characterization of uterine carcinosarcoma. Cancer Cell. 2017 Mar 13;31(3):411-423.
Goldstein et al. Genomic activation of PPARG reveals a candidate therapeutic axis in bladder cancer. Cancer Res. 2017 Sep 18. pii: canres.1701.2017.
Imielinski, Guo and Meyerson. Insertions and deletions target lineage-defining genes in human cancers. Cell. 2017 Jan 26;168(3):460-472.e14.
Lu et al. MET Exon 14 mutation encodes an actionable therapeutic target in lung adenocarcinoma. Cancer Res. 2017 Aug 15;77(16):4498-4505.
Robertson, Shih, Yau et al. Integrative analysis identifies four molecular and clinical subsets in uveal melanoma. Cancer Cell. 2017 Aug 14;32(2):204-220.e15.

2016

Berger, Brooks, Wu et al. High-throughput phenotyping of lung cancer somatic mutations. Cancer Cell. 2016 Aug 8;30(2):214-228.
Beroukhim, Zhang and Meyerson. Copy number alterations unmasked as enhancer hijackers. Nat Genet. 2016 Dec 28;49(1):5-6.
Campbell et al. Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas. Nat Genet. 2016 Jun;48(6):607-16.
Gannon et al. Identification of an "exceptional responder" cell line to MEK1 inhibition: Clcnical implications for MEK-targeted therapy. Mol Cancer Res. 2016 Feb;14(2):207-15.
Lin, Francis et al. Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets. Cancer Biol Ther. 2016 Dec;17(12):1274-1281.
Pedamallu, Bhatt, Bullman et al. Metagenomic Characterization of microbial communities In Situ within the deeper layers of the ileum in Crohn's disease. Cell Mol Gastroenterol Hepatol. 2016 May 26;2(5):563-566.e5.
Shankar et al. BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology. Acta Neuropathol. 2016 Jan;131(1):147-50.
de Waal et al. Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics. Nat Chem Biol. 2016 Feb;12(2):102-8.
Zhang et al. Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers. Nat Genet. 2016 Feb;48(2):176-82.

2015

Arvey et al. The tumor virus landscape of AIDS-related lymphomas. Blood. 2015 May 14;125(20):e14-22.
Bambury et al. DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors. BMC Cancer. 2015 Apr 9;15:242.
Berrios et al. Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors. J Virol. 2015 Jan;89(1):857-62.
Guo et al. Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma. Cancer Res. 2015 Jan 15;75(2):264-9.
Lin et al. Dynamic epigenetic regulation by menin during pancreatic islet tumor formation. Mol Cancer Res. 2015 Apr;13(4):689-98.
Ramos et al. Oncotator: cancer variant annotation tool. Hum Mutat. 2015 Apr;36(4):E2423-9.
Shankar, Francis et al. Rapid intraoperative molecular characterization of glioma. JAMA Oncol. 2015 Aug;1(5):662-7.
van de Wetering et al. Prospective derivation of a living organoid biobank of colorectal cancer patients. Cell. 2015 May 7;161(4):933-45.
Zhang et al. Calibrating genomic and allelic coverage bias in single-cell sequencing. Nat Commun. 2015 Apr 16;6:6822.
Zhang et al. Chromothripsis from DNA damage in micronuclei. Nature. 2015 June 11;522(7555):179-84.

2014

Berger, Imielinski et al. Oncogenic RIT1 mutations in lung adenocarcinoma. Oncogene. 2014 Aug 28;33(35):4418-23.
Bhatt et al. In search of a candidate pathogen for giant cell arteritis: Sequencing based characterization of the giant cell arteritis microbiome. Arthritis Rheumatol. 2014 Jul;66(7):1939-44.
Brooks et al. A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events. PLoS One. 2014 Jan 31;9(1):e87361.
Cancer Genome Atlas Research Network (M. Meyerson, corresponding author). Comprehensive molecular profiling of lung adenocarcinoma. Nature. 2014 Jul 31;511(7511):543-50.
Cho, Bass et al. Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab. Mol Cancer. 2014 Jun 4;13(1):141.
Choi & Meyerson. Targeted genomic rearrangements using CRISPR/Cas technology. Nat Commun. 2014 Apr 24;5:3728.
Francis, Zhang et al. EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing. Cancer Discov. 2014 Aug;4(8):956-71.
Helman et al. Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing. Genome Res. 2014 Jul;24(7):1053-63.
Hoadley et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell. 2014 Aug 14;158(4):929-44.
Imielinski, Greulich, Kaplan et al. Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma. J Clin Invest. 2014 Apr 1;124(4):1582-6.
Kim, Hammerman et al. Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients. J Clin Oncol. 2014 Jan 10;32(2):121-8.
Ojesina et al. Landscape of genomic alterations in cervical carcinomas. Nature. 2014 Feb 20;506(7488):371-5.
Parfenov, Pedamallu et al. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15544-9.
Pugh et al. Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences. Oncogene. 2014 Nov 6;33(45):5295-302.
Sharifnia et al. Genetic modifiers of EGFR dependence in non-small cell lung cancer. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18661-6. doi: 10.1073/pnas.1412228112.
TCGA. Comprehensive molecular profiling of lung adenocarcinoma. Nature. 2014 Jul 31;511(7511):543-50. doi: 10.1038/nature13385.
Watanabe et al. SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas. J Clin Invest. 2014 Apr 1;124(4):1636-45.

2013

Abazeed et al. Integrative radiogenomic profiling of squamous cell lung cancer. Cancer Res. 2013 Oct 15;73(20):6289-98.
Bhatt, Freeman et al. Sequence-based discovery of Bradyrhizobium enterica in cord colitis syndrome. New Engl J Med. 2013 Aug 8;369(6):517-28.
Chmielecki et al. Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors. Nat Genet. 2013 Feb;45(2):131-2.
Cho et al. Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization. Cancer Res. 2013 Nov 15;73(22):6770-9.
Francis et al. Somatic mutation of CDKN1B in small intestine neuroendocrine tumors. Nat Genet. 2013 Dec;45(12):1483-6.
Kostic et al. Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment. Cell Host Microbe. 2013 Aug 14;14(2):207-15.
Liao et al. Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. Cancer Res. 2013 Aug 15;73(16):5195-205.
Pugh et al. The genetic landscape of high-risk neuroblastoma. Nat Genet. 2013 Mar;45(3):279-84.
Verhaak et al. Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. J Clin Invest. 2013 Jan 2;123(1):517-25.
Watanabe, Francis et al. Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target. Genes Dev. 2013 Jan 15;27(2):197-210.
Zack et al. Pan-cancer patterns of somatic copy number alteration. Nat Genet. 2013 Sep 26;45(10):1134-40.

2012

Banerji et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature. 2012 Jun 20;486(7403):405-9.
Cancer Genome Atlas Research Network (M. Meyerson, corresponding author). Comprehensive genomic characterization of squamous cell lung cancers. Nature. 2012 Sep 27;489(7417):519-25.

Carter et al. Absolute quantification of somatic DNA alterations in human cancer. Nat Biotechnol. 2012 May;30(5):413-21.
Greulich et al. Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14476-81.
Imielinski et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell. 2012 Sep 14;150(6):1107-20.

Kostic et al. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res. 2012 Feb;22(2):292-8. doi: 10.1101/gr.126573.111.
Pugh et al. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature. 2012 Aug 2;488(7409):106-10.

TCGA. Comprehensive genomic characterization of squamous cell lung cancers. Nature. 2012 Sep 27;489(7417):519-25. doi: 10.1038/nature11404.

2011

Bass et al. Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nat Genet. 2011 Sep 4;43(10):964-8.
Cho et al. Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies. Cancer Res. 2011 Dec 15;71(24):7587-96.
Dutt et al. Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. PLoS One. 2011;6(6):e20351.
Francis et al. The menin tumor suppressor protein is phosphorylated in response to DNA damage. PLoS One. 2011 Jan 14;6(1):e16119.

Hammerman et al. Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discov. 2011 Jun;1(1):78-89.
Kostic et al. PathSeq: software to identify or discover microbes by deep sequencing of human tissue. Nat Biotechnol. 2011 May;29(5):393-6.
Lin et al. Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13379-86.

Mermel et al. GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biol. 2011;12(4):R41.

2010

Barretina et al. Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nat Genet. 2010 Aug;42(8):715-21.
Beroukhim et al. The landscape of somatic copy-number alteration across human cancers. Nature. 2010 Feb 18;463(7283):899-905.
Verhaak et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 2010 Jan 19;17(1):98-110.

2009

Bass et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet. 2009 Nov;41(11):1238-42.
Beroukhim et al. Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer Res. 2009 Jun 1;69(11):4674-81.
Chiang et al. High-resolution mapping of copy-number alterations with massively parallel sequencing. Nat Methods. 2009 Jan;6(1):99-103.

Ramos et al. Amplification of chromosomal segment 4q12 in non-small cell lung cancer. Cancer Biol Ther. 2009 Nov;8(21):2042-50.
Rozenblatt-Rosen et al. The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors. Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):755-60.

2008

Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008 Oct 23;455(7216):1061-8.
Chiang et al. Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer Res. 2008 Aug 15;68(16):6779-88.
Ding et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 2008 Oct 23;455(7216):1069-75.
Dutt et al. Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8713-7.

George et al. Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature. 2008 Oct 16;455(7215):975-8.
Li et al. Major copy proportion analysis of tumor samples using SNP arrays. BMC Bioinformatics. 2008 Apr 21;9:204.

2007

Minami et al. The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272. Oncogene. 2007 Jul 26;26(34):5023-7.
Thomas et al. High-throughput oncogene mutation profiling in human cancer. Nat Genet. 2007 Mar;39(3):347-51.
Weir et al. Characterizing the cancer genome in lung adenocarcinoma. Nature. 2007 Dec 6;450(7171):893-8.

Yuza et al. Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors. Cancer Biol Ther. 2007 May;6(5):661-7.

2006

Hayes et al. Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts. J Clin Oncol. 2006 Nov 1;24(31):5079-90.
Ji et al. Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7817-22.
Lee et al. Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain. PLoS Med. 2006 Dec;3(12):e485.

MacConaill et al. Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583. Mol Cancer Res. 2006 Oct;4(10):793-801.
Thomas et al. Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing. Nat Med. 2006 Jul;12(7):852-5.

2005

Greulich et al. Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants. PLoS Med. 2005 Nov;2(11):e313.
LaFramboise et al. Allele-specific amplification in cancer revealed by SNP array analysis. PLoS Comput Biol. 2005 Nov;1(6):e65.

Rozenblatt-Rosen et al. The parafibromin tumor suppressor protein is part of a human Paf1 complex. Mol Cell Biol. 2005 Jan;25(2):612-20.

Thomas et al. Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors. Cold Spring Harb Symp Quant Biol. 2005;70:73-81.

Zhao et al. Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Res. 2005 Jul 1;65(13):5561-70.

2004

Hughes et al. Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. Mol Cell. 2004 Feb 27;13(4):587-97.
Jänne et al. High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines. Oncogene. 2004 Apr 8;23(15):2716-26.
Paez et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004 Jun 4;304(5676):1497-500.
Scacheri et al. Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1892-7.
Tengs et al. Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments. Nucleic Acids Res. 2004 Aug 25;32(15):e121.
Zhao et al. An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Res. 2004 May 1;64(9):3060-71.

2000-2003

Bhattacharjee A, Richards WG, Staunton J, Li C, Monti S, Vasa P, Ladd C, Beheshti J, Bueno R, Gillette M, Loda M, Weber G, Mark EJ, Lander ES, Wong W, Johnson BE, Golub TR, Sugarbaker DJ, Meyerson M. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13790-5.
Lindblad-Toh K, Tanenbaum DM, Daly MJ, Winchester E, Lui WO, Villapakkam A, Stanton SE, Larsson C, Hudson TJ, Johnson BE, Lander ES, Meyerson M. Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays. Nat Biotechnol. 2000 Sep;18(9):1001-5.
Naoki K, Chen TH, Richards WG, Sugarbaker DJ, Meyerson M. Missense mutations of the BRAF gene in human lung adenocarcinoma. Cancer Res. 2002 Dec 1;62(23):7001-3.
Stanton SE, Shin SW, Johnson BE, Meyerson M. Recurrent allelic deletions of chromosome arms 15q and 16q in human small cell lung carcinomas. Genes Chromosomes Cancer. 2000 Mar;27(3):323-31.
Weber G, Shendure J, Tanenbaum DM, Church GM, Meyerson M. Identification of foreign gene sequences by transcript filtering against the human genome. Nat Genet. 2002 Feb;30(2):141-2.
Xu Y, Stange-Thomann N, Weber G, Bo R, Dodge S, David RG, Foley K, Beheshti J, Harris NL, Birren B, Lander ES, Meyerson M. Pathogen discovery from human tissue by sequence-based computational subtraction. Genomics. 2003 Mar;81(3):329-35.

Pre-2000

Counter CM, Meyerson M, Eaton EN, Ellisen LW, Caddle SD, Haber DA, Weinberg RA. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene. 1998 Mar 5;16(9):1217-22.
Counter CM, Meyerson M, Eaton EN, Weinberg RA. The catalytic subunit of yeast telomerase. Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9202-7.
Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersbergen RL, Knoll JH, Meyerson M, Weinberg RA. Inhibition of telomerase limits the growth of human cancer cells. Nat Med. 1999 Oct;5(10):1164-70.
Kolquist KA, Ellisen LW, Counter CM, Meyerson M, Tan LK, Weinberg RA, Haber DA, Gerald WL. Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. Nat Genet. 1998 Jun;19(2):182-6.

Meyerson M, Enders GH, Wu CL, Su LK, Gorka C, Nelson C, Harlow E, Tsai LH. A family of human cdc2-related protein kinases. EMBO J. 1992 Aug;11(8):2909-17.
Meyerson M, Counter CM, Eaton EN, Ellisen LW, Steiner P, Caddle SD, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell. 1997 Aug 22;90(4):785-95.
Meyerson M, Harlow E. Identification of G1 kinase activity for cdk6, a novel cyclin D partner. Mol Cell Biol. 1994 Mar;14(3):2077-86.
Meyerson M, Faha B, Su LK, Harlow E, Tsai LH. The cyclin-dependent kinase family. Cold Spring Harb Symp Quant Biol. 1991;56:177-86.
Meyerson M. Telomerase enzyme activation and human cell immortalization. Toxicol Lett. 1998 Dec 28;102-103:41-5.

Tsai LH, Harlow E, Meyerson M. Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. Nature. 1991 Sep12;353(6340):174-7.