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Meyerson Lab - Cancer Genomics and Genome-Inspired Discovery

Meyerson Laboratory
CANCER GENOMICS AND GENOME-INSPIRED DISCOVERY

New paper on SARS-CoV-2 transcriptomes!

Jason Nomburg, a joint graduate student with Dr. Meyerson and Dr. James DeCaprio, conducted an integrative analysis of SARS-CoV-2 transcriptomes to characterize the RNA species present during infection. Jason found that SARS-CoV-2 produces non-canonical RNA species in a variety of different infection settings. These alternative transcripts may be important in the virus life cycle.  Read the paper here!
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New paper on relationship of Native American ancestry and EGFR mutations
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Jian Carrot-Zhang, post-doctoral fellow, and colleagues developed a new technique to compare somatic genome alterations with ancestry analyses using tumor-only sequence data, working with Dr. Sasha Gusev in Dana-Farber’s Data Sciences Department. By studying 1,153 lung cancers from Latin American patients, in collaboration with Dr. Andres Cardona in Bogota, Colombia, and Dr. Oscar Arrieta in Mexico City, they determined that Native American ancestry in this patient population was associated with increased EGFR mutation frequency, regardless of smoking status. From this work, we can deepen our understanding of potential lung cancer risk factors. Next steps: see if we can find an inherited locus.  Read the paper here!
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Matthew Meyerson elected as a Fellow of the American Association for the Advancement of Science

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Matthew Meyerson was elected as a Fellow by the AAAS Council for his significant contributions to the advancement of science or its applications. Fellows are selected from a diverse array of fields, including technology, academia, research, and government. Read more about the honor here!
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