New Ileal NETs paper

​Zhouwei and Netta studied synchronous primary ileal neuroendocrine tumors (NETs) to identify recurrent copy-number alterations. They confirmed that chromosome ​(chr) 18 loss of heterozygosity (LOH) is the most common copy-number alteration. Interestingly, they identified three different chr18 LOH patterns in different tumors from the same patients. These different chr18 LOH patterns suggest that synchronous primary ileal NETs are likely to develop independently, via a mechanism that is not currently understood.