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Meyerson Lab

Genome Discovery in Other Cancers

Besides lung cancer, our group has also contributed to discovery of novel genomic alterations in a variety of other tumor types.
  • Discovery of mutations in JAK2 in polycythemia vera (Levine et al., Cancer Cell, 2005)
  • Mutations in FGFR2 in endometrial carcinoma (Dutt et al., Proc Natl Acad Sci USA, 2008)
  • Discovery of VTI1A-TCF7L2 translocations in colon cancer (Bass et al., Nat. Genetics, 2011)
  • DDX3X mutations in medulloblastoma (Pugh et al., Nature, 2012)
  • Development of a prognostic model for classification of high grade ovarian carcinoma (Verhaak et al., J Clin Investig, 2013)
  • ALK mutations in neuroblastoma (George et al., Nature, 2008; Pugh et al., Nat. Genetics, 2013)
  • Uncovering NAB2-STAT6 fusions in solitary fibrous tumors (Chmielecki et al., Nat. Genetics, 2013)
  • Alterations in CDKN1B in carcinoid tumors (Francis et al., Nat. Genetics, 2013)
  • Uncovering novel EGFR variants in glioblastoma (Lee et al., PLoS Med, 2006; Francis et al., Cancer Discov, 2014)
  • Mutations in MAPK, ELF3, and HLA in cervical carcinomas (Ojesina et al., Nature, 2014)
  • Role of the MEN1 and RBP genes in pancreatic neuroendocrine tumors (Lin et al., Proc Natl Acad Sci USA, 2011; Lin et al., Mol Cancer Res., 2015)​​​​

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